REAL

Prevalence of Helicobacter pylori is still high among symptomatic Bulgarian children

Boyanova, Lyudmila and Hadzhiyski, Petyo and Markovska, Rumyana and Yaneva, Penka and Yordanov, Daniel and Gergova, Galina and Mitov, Ivan (2018) Prevalence of Helicobacter pylori is still high among symptomatic Bulgarian children. Acta Microbiologica et Immunologica Hungarica, 66 (2). pp. 255-260. ISSN 1217-8950

[img]
Preview
Text
030.65.2018.053.pdf

Download (62kB) | Preview

Abstract

Helicobacter pylori positivity was assessed among 656 symptomatic children in 2010–2017. Overall infection prevalence was 24.5% and a significantly higher rate was detected in girls (28.5%) compared to boys (20.0%). Moreover, in children with duodenal ulcer, H. pylori prevalence was higher (47.4%) compared with the rest (23.9%). On the contrary, the infection was detected 1.9-fold less frequently in patients with GERD (14.5%) compared with the other (27.0%) patients and 2.1-fold less often in the presence of duodenogastric reflux (bile) reflux (13.0%) compared with the absence of the reflux (27.0%). No significant difference was observed between the younger (aged ≤7 years, 20.0%) and the older (aged 8–18 years, 25.5%) patients. H. pylori infection rate in Bulgarian pediatric patients between 2010 and 2017 was 2.5-fold lower than that in 1996–2006. In conclusion, H. pylori infection is still an important concern for Bulgarian children, although having decreased by about 1.8%/yearly over 21 years. This study reveals the importance of H. pylori diagnostics even in the youngest symptomatic children and demonstrates an inverse association between either GERD or bile reflux and H. pylori infection.

Item Type: Article
Subjects: Q Science / természettudomány > QR Microbiology / mikrobiológia
Depositing User: Ágnes Sallai
Date Deposited: 02 Aug 2019 07:52
Last Modified: 31 Dec 2019 00:40
URI: http://real.mtak.hu/id/eprint/94869

Actions (login required)

Edit Item Edit Item