Remete, Attila Márió and Nonn, Melinda and Fustero, Santos and Haukka, Matti and Fülöp, Ferenc and Kiss, Loránd (2017) Fluorination of some highly functionalized cycloalkanes: chemoselectivity and substrate dependence. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 13. pp. 2364-2371. ISSN 1860-5397
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Abstract
A study exploring the chemical behavior of some dihydroxylated beta-amino ester stereo-and regioisomers, derived from unsaturated cyclic beta-amino acids is described. The nucleophilic fluorinations involving hydroxy-fluorine exchange of some highly functionalized alicyclic diol derivatives have been carried out in view of selective fluorination, investigating substrate dependence, neighboring group assistance and chemodifferentiation.
| Item Type: | Article |
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| Additional Information: | Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, Szeged, H-6720, Hungary MTA-SZTE Stereochemistry Research Group, Hungarian Academy of Sciences, Eötvös u. 6, Szeged, H-6720, Hungary Departamento de Química Orgánica, Facultad de Farmàcia, Universidad de Valencia, Av. Vicente Andrés Estellés, s/n, Valencia, 46100, Spain Department of Chemistry, University of Jyväskylä, Jyväskylä, FIN-40014, Finland Cited By :3 Export Date: 7 December 2018 CODEN: BJOCB Correspondence Address: Fülöp, F.; Institute of Pharmaceutical Chemistry, University of Szeged, Eötvös u. 6, Hungary; email: fulop@pharm.u-szeged.hu |
| Uncontrolled Keywords: | DERIVATIVES; ANALOGS; BETA-AMINO ACIDS; STEREOSELECTIVE-SYNTHESIS; CONFORMATIONAL-ANALYSIS; amino acids; CHEMOSELECTIVITY; STEREOISOMERS; ACCESS; fluorine; FUNCTIONALIZATION; |
| Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 10 Sep 2019 13:56 |
| Last Modified: | 10 Sep 2019 13:56 |
| URI: | http://real.mtak.hu/id/eprint/99006 |
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