Items where Author is "Hetényi, Csaba"

Article

Balázs, Orsolya and Dombi, Ágnes and Zsidó, Balázs Zoltán and Hetényi, Csaba and Vida, Róbert György and Poór, Miklós (2023) Probing the Interactions of 31 Mycotoxins with Xanthine Oxidase: Alternariol, Alternariol-3-Sulfate, and α-Zearalenol Are Allosteric Inhibitors of the Enzyme. TOXINS, 15 (4). No-250. ISSN 2072-6651

Börzsei, Rita and Borbély, Éva and Kántás, Boglárka and Hudhud, Lina and Horváth, Ádám and Szőke, Éva and Hetényi, Csaba and Helyes, Zsuzsanna and Pintér, Erika (2023) The Heptapeptide Somatostatin Analogue TT-232 Exerts Analgesic and Anti-Inflammatory Actions via SST4 Receptor Activation: in silico, in vitro and in vivo Evidence in Mice. BIOCHEMICAL PHARMACOLOGY, 209. No.-115419. ISSN 0006-2952 (print); 1873-2968 (online)

Csenki, Zsolt and Bartók, Tibor and Bock, Illés and Horváth, Levente and Lemli, Beáta and Zsidó, Balázs Zoltán and Angeli, Cserne and Hetényi, Csaba and Szabó, István and Urbányi, Béla and Kovács, Melinda and Poór, Miklós (2023) Interaction of Fumonisin B1, N-Palmitoyl-Fumonisin B1, 5-O-Palmitoyl-Fumonisin B1, and Fumonisin B4 Mycotoxins with Human Serum Albumin and Their Toxic Impacts on Zebrafish Embryos. BIOMOLECULES, 13 (5). No.-755. ISSN 2218-273X

Fliszár-Nyúl, Eszter and Faisal, Zelma and Skaper, Renáta and Lemli, Beáta and Bayartsetseg, Bayarsaikhan and Hetényi, Csaba and Gömbös, Patrik and Szabó, András and Poór, Miklós (2022) Interaction of the Emerging Mycotoxins Beauvericin, Cyclopiazonic Acid, and Sterigmatocystin with Human Serum Albumin. BIOMOLECULES. ISSN 2218-273X

Bálint, Mónika and Zsidó, Balázs Zoltán and van der Spoel, David and Hetényi, Csaba (2022) Binding Networks Identify Targetable Protein Pockets for Mechanism-Based Drug Design. International Journal of Molecular Sciences, 23 (13). No. 7313. ISSN 1422-0067

Börzsei, Rita and Zsidó, Balázs Zoltán and Bálint, Mónika and Helyes, Zsuzsanna and Pintér, Erika and Hetényi, Csaba (2022) Exploration of Somatostatin Binding Mechanism to Somatostatin Receptor Subtype 4. International Journal of Molecular Sciences, 23 (13). No. 6878. ISSN 1422-0067

Fliszár-Nyúl, Eszter and Faisal, Zelma and Skaper, Renáta and Lemli, Beáta and Bayartsetseg, Bayarsaikhan and Hetényi, Csaba and Gömbös, Patrik and Szabó, András and Poór, Miklós (2022) Interaction of the Emerging Mycotoxins Beauvericin, Cyclopiazonic Acid, and Sterigmatocystin with Human Serum Albumin. Biomolecules, 12 (8). No. 1106. ISSN 2218-273X

Lemli, Beáta and Vilmányi, Péter and Fliszár-Nyúl, Eszter and Zsidó, Balázs Zoltán and Hetényi, Csaba and Szente, Lajos and Poór, Miklós (2022) Testing Serum Albumins and Cyclodextrins as Potential Binders of the Mycotoxin Metabolites Alternariol-3-Sulfate, Alternariol-9-Monomethylether and Alternariol-9-Monomethylether-3-Sulfate. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (22). No.-14353. ISSN 1661-6596 (print); 1422-0067 (online)

Zsidó, Balázs Zoltán and Börzsei, Rita and Szél, Viktor and Hetényi, Csaba (2021) Determination of Ligand Binding Modes in Hydrated Viral Ion Channels to Foster Drug Design and Repositioning. JOURNAL OF CHEMICAL INFORMATION AND MODELING, 61 (8). pp. 4011-4022. ISSN 1549-9596

Kántás, Boglárka and Szőke, Éva and Börzsei, Rita and Bánhegyi, Péter and Asghar, Junaid and Hudhud, Lina and Steib, Anita and Hunyady, Ágnes and Horváth, Ádám and Kecskés, Angéla and Borbély, Éva and Hetényi, Csaba and Pethő, Gábor and Pintér, Erika and Helyes, Zsuzsanna (2021) In Silico, In Vitro and In Vivo Pharmacodynamic Characterization of Novel Analgesic Drug Candidate Somatostatin SST4 Receptor Agonists. FRONTIERS IN PHARMACOLOGY, 11. ISSN 1663-9812

Fliszár-Nyúl, Eszter and Faisal, Zelma and Mohos, Violetta and Derdák, Diána and Lemli, Beáta and Kálai, Tamás and Sár, Cecília and Zsidó, Balázs Z. and Hetényi, Csaba and Horváth, Ádám I. and Helyes, Zsuzsanna and Deme, Ruth and Bogdán, Dóra and Czompa, Andrea and Mátyus, Péter and Poór, Miklós (2021) Interaction of SZV 1287, a novel oxime analgesic drug candidate, and its metabolites with serum albumin. JOURNAL OF MOLECULAR LIQUIDS, 333. p. 115945. ISSN 0167-7322

Zsidó, Balázs Zoltán and Börzsei, Rita and Pintér, Erika and Hetényi, Csaba (2021) Prerequisite Binding Modes Determine the Dynamics of Action of Covalent Agonists of Ion Channel TRPA1. Pharmaceuticals, 14 (10). No. 988. ISSN 1424-8247

Zsidó, Balázs Zoltán and Hetényi, Csaba (2021) The role of water in ligand binding. CURRENT OPINION IN STRUCTURAL BIOLOGY, 67. pp. 1-8. ISSN 0959-440X

Mohos, Violetta and Fliszár-Nyúl, Eszter and Ungvári, Orsolya and Bakos, Éva and Kuffa, Katalin and Bencsik, Tímea and Zsidó, Balázs Zoltán and Hetényi, Csaba and Telbisz, Ágnes and Özvegy-Laczka, Csilla and Poór, Miklós (2020) Effects of chrysin and its major conjugated metabolites chrysin-7-sulfate and chrysin-7-glucuronide on cytochrome P450 enzymes, and on OATP, P-gp, BCRP and MRP2 transporters. DRUG METABOLISM AND DISPOSITION, 48 (9). pp. 1-45. ISSN 0090-9556 (print); 1521-009X (online)

Zsidó, Balázs Zoltán and Hetényi, Csaba (2020) Molecular Structure, Binding Affinity, and Biological Activity in the Epigenome. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (11). p. 4134. ISSN 1422-0067

Parker, Benjamin W. and Gogl, Gergo and Bálint, Mónika and Hetényi, Csaba and Reményi, Attila and Weiss, Eric L. (2020) Ndr/Lats Kinases Bind Specific Mob-Family Coactivators through a Conserved and Modular Interface. BIOCHEMISTRY, 59 (17). pp. 1688-1700. ISSN 0006-2960

Szőke, Éva and Bálint, Mónika and Hetényi, Csaba and Markovics, Adrienn and Elekes, Krisztián and Pozsgai, Gábor and Szűts, Tamás and Kéri, György and Őrfi, László and Sándor, Zoltán and Szolcsányi, János and Pintér, Erika and Helyes, Zsuzsanna (2020) Small molecule somatostatin receptor subtype 4 (sst4) agonists are novel anti-inflammatory and analgesic drug candidates. NEUROPHARMACOLOGY, 178. p. 108198. ISSN 0028-3908

Zsidó, Balázs Zoltán and Balog, Mária and Erős, Nikolett and Poór, Miklós and Mohos, Violetta and Fliszár-Nyúl, Eszter and Hetényi, Csaba and Nagane, Masaki and Hideg, Kálmán and Kálai, Tamás and Bognár, Balázs (2020) Synthesis of Spin-Labelled Bergamottin: A Potent CYP3A4 Inhibitor with Antiproliferative Activity. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21 (2). p. 508. ISSN 1422-0067

Mohos, Violetta and Fliszár-Nyúl, Eszter and Lemli, Beáta and Zsidó, Balázs Zoltán and Hetényi, Csaba and Mladěnka, Přemysl and Horký, Pavel and Pour, Milan and Poór, Miklós (2020) Testing the Pharmacokinetic Interactions of 24 Colonic Flavonoid Metabolites with Human Serum Albumin and Cytochrome P450 Enzymes. Biomolecules, 10 (3). p. 409. ISSN 2218-273X

Horváth, István and Jeszenői, Norbert and Bálint, Mónika and Paragi, Gábor and Hetényi, Csaba (2019) A Fragmenting Protocol with Explicit Hydration for Calculation of Binding Enthalpies of Target-Ligand Complexes at a Quantum Mechanical Level. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20 (18). p. 4384. ISSN 1422-0067

Faisal, Zelma and Vörös, Virág and Lemli, Beáta and Derdák, Diána and Kunsági-Máté, Sándor and Bálint, Mónika and Hetényi, Csaba and Csepregi, Rita and Kőszegi, Tamás and Bergmann, Dominik and Sueck, Franziska and Humpf, Hans-Ulrich and Hübner, Florian and Poór, Miklós (2019) Interaction of the mycotoxin metabolite dihydrocitrinone with serum albumin. Mycotoxin Research, 35 (2). pp. 129-139. ISSN 0178-7888, ESSN: 1867-1632

Kántás, Boglárka and Börzsei, Rita and Szőke, Éva and Bánhegyi, Péter and Horváth, Ádám and Hunyady, Ágnes and Borbély, Éva and Hetényi, Csaba and Pintér, Erika and Helyes, Zsuzsanna (2019) Novel Drug-Like Somatostatin Receptor 4 Agonists are Potential Analgesics for Neuropathic Pain. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20 (24). p. 6245. ISSN 1422-0067

Faisal, Zelma and Derdák, Diána and Lemli, Beáta and Kunsági-Máté, Sándor and Bálint, Mónika and Hetényi, Csaba and Csepregi, Rita and Kőszegi, Tamás and Sueck, Franziska and Cramer, Benedikt and Humpf, Hans-Ulrich and Poór, Miklós (2018) Interaction of 2′R-ochratoxin A with Serum Albumins: Binding Site, Effects of Site Markers, Thermodynamics, Species Differences of Albumin-binding, and Influence of Albumin on Its Toxicity in MDCK Cells. Toxins, 10 (9). p. 353. ISSN 2072-6651

Faisal, Zelma and Lemli, Beáta and Szerencsés, Dénes and Kunsági-Máté, Sándor and Bálint, Mónika and Hetényi, Csaba and Kuzma, Mónika and Mayer, Mátyás and Poór, Miklós (2018) Interactions of zearalenone and its reduced metabolites α-zearalenol and β-zearalenol with serum albumins: species differences, binding sites, and thermodynamics. Mycotoxin Research. ISSN 0178-7888, ESSN: 1867-1632

Poór, Miklós and Bálint, Mónika and Hetényi, Csaba and Gődér, Beatrix and Kunsági-Máté, Sándor and Kőszegi, Tamás and Lemli, Beáta (2017) Investigation of Non-Covalent Interactions of Aflatoxins (B1, B2, G1, G2, and M1) with Serum Albumin. Toxins, 9 (11). p. 339. ISSN 2072-6651

Ecsédi, Péter and Kiss, Bence and Gógl, Gergő and Radnai, László and Buday, László and Koprivanecz, Kitti and Liliom, Károly and Leveles, Ibolya and Vértessy G., Beáta and Jeszenői, Norbert and Hetényi, Csaba and Schlosser, Gitta (Vácziné) and Katona, Gergely and Nyitray, László (2017) Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding. STRUCTURE, 25. p. 1. ISSN 0969-2126

Alexa, Anita and Gógl, Gergő and Glatz, Gábor and Garai, Ágnes and Zeke, András and Hetényi, Csaba and Reményi, Attila (2015) Structural assembly of the signaling competent ERK2-RSK1 heterodimeric protein kinase complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112 (9). pp. 2711-6. ISSN 0027-8424

Gógl, Gergő and Schneider, Kyle D. and Yeh, Brian J. and Alam, Nashida and Nguyen Ba, Alex N. and Hetényi, Csaba and Reményi, Attila (2015) The structure of an NDR/LATS kinase – mob complex reveals a novel kinase-coactivator system and substrate docking mechanism. PLOS BIOLOGY, 13 (5). e1002146. ISSN 1544-9173

Bodor, Andrea and Radnai, László and Hetényi, Csaba and Rapali, Péter and Láng, András and Kövér, E. Katalin and Perczel, András and Wahlgren, Y. Weixiao and Katona, Gergely and Nyitray, László (2014) DYNLL2 dynein light chain binds to an extended linear motif of myosin 5a tail that has structural plasticity. BIOCHEMISTRY, 53. pp. 7107-7122. ISSN 0006-2960

Zhang, Haiyang and Tan, Tianwei and Hetényi, Csaba and Spoel, David (2013) Quantification of Solvent Contribution to the Stability of Noncovalent Complexes. Journal of Chemical Theory and Computation, 10 (9). A/4542-J/4551. ISSN 1549-9618 (Submitted)

Berkesi, Ottó and Körtvélyesi, Tamás and Hetényi, Csaba and Németh, Tamás and Pálinkó, István (2003) Hydrogen bonding interactions of benzylidene type Schiff bases studied by vibrational spectroscopic and computational methods. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 5 (10). pp. 2009-2014. ISSN 1463-9076

Book Section

Hetényi, Csaba and Bálint, Mónika (2020) Systematic Exploration of Binding Modes of Ligands on Drug Targets. In: Structural Bioinformatics. Humana Press, New York, pp. 107-121.

Monograph

Nyitray, László and Hegyi, György and Hetényi, Csaba and Hódi, Zsuzsanna and Kovács, Mihály and Málnási Csizmadia, András and Perczel, András and Schlett, Katalin and Tárnok, Krisztián and Tóth, Judit (2011) Miozin motorfehérjék: szerkezet-funkció összefüggések és funkcionális vizsgálatok idegsejteken = Myosin motor proteins: structure-function relationship and functional studies in neurons. Project Report. OTKA.

Gráf, László and Gombos, Linda and Hegyi, György and Hetényi, Csaba and Hódi, Zsuzsanna and Kellermayer, Miklós Sándor Zoltán and Láng, András and Málnási Csizmadia, András and Németh, Attila and Nyitray, László and Pál, Gábor and Patthy, András and Perczel, András and Szilágyi, László and Venekei, István (2009) A fehérje-fehérje kölcsönhatások szerkezeti alapjai és biológiai szerepük: multidiszciplináris megközelítés = The structural basis and biological role of protein-protein interactions: a multidisciplinary approach. Project Report. OTKA.

Conference or Workshop Item

Zsidó, Balázs Zoltán and Börzsei, Rita and Hetényi, Csaba (2019) From Protein Complexes to Synaptic Connections and Cell Communities, Cellular Interactions. In: From Protein Complexes to Synaptic Connections and Cell Communities, Cellular Interactions, 27-29 October 2019, Budapest - Esztergom.