Continuous Flow Esterification of a H-Phosphinic Acid, and Transesterification of H-Phosphinates and H-Phosphonates under Microwave Conditions

Kiss, Nóra Zsuzsa and Henyecz, Réka and Keglevich, György (2020) Continuous Flow Esterification of a H-Phosphinic Acid, and Transesterification of H-Phosphinates and H-Phosphonates under Microwave Conditions. MOLECULES, 25 (3). pp. 719-734. ISSN 1420-3049

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Abstract

The microwave (MW)-assisted direct esterification of phenyl-H-phosphinic acid, transesterification of the alkyl phenyl-H-phosphinates so obtained, and the similar reaction of dibenzyl phosphite (DBP) were investigated in detail, and the batch accomplishments were translated into a continuous flow operation that, after optimization of the parameters, such as temperature and flow rate, proved to be more productive. Alcoholysis of DBP is a two-step process involving an intermediate phosphite with two di�erent alkoxy groups. The latter species are of synthetic interest, as precursors for optically active reagents.

Item Type:	Article
Subjects:	Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User:	Dr. Nóra Zsuzsa Mireiszné Kiss
Date Deposited:	15 Sep 2020 13:56
Last Modified:	03 Apr 2023 06:55
URI:	http://real.mtak.hu/id/eprint/113296

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• Continuous Flow Esterification of a H-Phosphinic Acid, and Transesterification of H-Phosphinates and H-Phosphonates under Microwave Conditions. (deposited 15 Sep 2020 13:56) [Currently Displayed]

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