Kovács, Ervin and Cseri, Levente and Jancsó, Attila and Terényi, Ferenc and Fülöp, Anna and Rózsa, Balázs and Galbács, Gábor and Mucsi, Zoltán (2021) Synthesis and Fluorescence Mechanism of the Aminoimidazolone Analogues of the Green Fluorescent Protein: Towards Advanced Dyes with Enhanced Stokes Shift, Quantum Yield and Two‐Photon Absorption. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2021 (41). pp. 5649-5660. ISSN 1434-193X
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Eur J Org Chem - 2021 - Kov cs - Synthesis and Fluorescence Mechanism of the Aminoimidazolone Analogues of the Green.pdf Available under License Creative Commons Attribution. Download (3MB) | Preview |
Abstract
Intramolecularly hydrogen-bonded analogues of the green fluorescence protein chromophore with an aminoimidazole moiety were synthesised and characterised. The fluorescence mechanism and substituent effects were investigated in a combined experimental-computational approach, and a 279-fold improvement in the quantum yield was realised. The novel compounds exhibit promising two-photon fluorescence for bioimaging applications.
| Item Type: | Article |
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| Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
| Depositing User: | Dr. Zoltán Mucsi |
| Date Deposited: | 29 Sep 2022 06:32 |
| Last Modified: | 03 Apr 2023 08:04 |
| URI: | http://real.mtak.hu/id/eprint/150484 |
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