A propolisz különböző kivonatainak in vivo hatékonysága brojlercsirke szalmonellózisa esetén = In vivo Efficacy of Different Extracts of Propolis in Broiler Salmonellosis

Olasz, Ákos and Jerzsele, Ákos and Balta, László and Dobra, Péter Ferenc and Kerek, Ádám (2023) A propolisz különböző kivonatainak in vivo hatékonysága brojlercsirke szalmonellózisa esetén = In vivo Efficacy of Different Extracts of Propolis in Broiler Salmonellosis. MAGYAR ÁLLATORVOSOK LAPJA, 145 (8). pp. 461-475. ISSN 0025-004X

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Abstract

A terjedő antimikrobiális rezisztencia következtében egyre nagyobb hangsúlyt kap az antibiotikumalternatívák fejlesztése és alkalmazása. Ilyen pl. a propolisz, amely a méhek által készített természetes bakteriosztatikus vagy baktericid hatásmódú anyag. Vizsgálatukban a szerzők a propolisz brojlercsirkék szalmonellózisának megelőzésében és kezelésében betöltött lehetséges szerepét vizsgálták. Kimutatták, hogy a propolisz szignifikánsan nem befolyásolja a testtömeg-gyarapodást, ill. a fajlagos takarmányértékesítést a kontrollhoz képest, de csökkenti a szalmonellózis megeredésének esélyét. Kijelenthető, hogy a propolisz biztonságosan alkalmazható takarmánykiegészítő brojlercsirkék számára. Background: The growing antimicrobial resistance could lead to up to 10 million human death cases per year by mid-century on current trends. The role of antibiotic use in animal health is without doubt, so alternatives to antibiotics have emerging importance in the veterinary field. Antibiotic alternatives include propolis, which has a proven immunomodulatory and bacteriostatic or bactericidal effect, depending on the bacteria. Salmonella enterica, known as the most common foodborne pathogen, is usually transmitted by eggs and poultry meat. From a human and animal health perspective, there is a lot of research defining its in vitro efficacy, but the in vivo efficacy of propolis is a less researched area. Objectives: To test the activity of Hungarian propolis against salmonellosis in broiler chickens. Materials and Methods: In our studies, doses of propolis dried via alcoholic extraction were administered 1×, 3× and 5× in feed and aqueous extract in drinking water. During rearing, daily weight gain was measured individually and feed consumption was measured in groups. In addition, the treated groups were infected by S. enterica strains. Results and Discussion: It was shown that although there was no significant difference in the weight gain between the control and treated groups, the weight gain of the treated groups was professionally relevantly higher than that of the control group during the first two weeks. Until day 12 of life, the groups treated with propolis extract consumed much less feed than the control group, and their weight gain exceeded that of the control group. This trend decreased until day 24. The feed conversion of the aqueous extract group was better than that of the control group for most of the study period. The feeding of propolis did not result in an earlier cessation of Salmonella shedding but did reduce the likelihood of clinical signs of infection. Based on our results, we can conclude that propolis can be safely used as a supplementary treatment for broiler chickens, significantly improving economic indicators during certain periods of the rearing period. In the future, it is worthwhile to conduct more studies with larger numbers of animals to investigate the efficacy and pharmacokinetic properties of propolis.

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