Treatment effects and adherence of sexually compulsive men in a randomized controlled trial of psychotherapy and medication

Scanavino, Marco D. T. and Guirado, Alia Garrudo and Marques, João Miguel and Amaral, Maria Luiza Sant'Ana do and Messina, Bruna and Reis, Sirlene Caramello dos and Barros, Vivian Boschesi and Abdo, Carmita Helena Najjar and Tavares, Hermano and Parsons, Jeffrey T. (2023) Treatment effects and adherence of sexually compulsive men in a randomized controlled trial of psychotherapy and medication. Journal of Behavioral Addictions, 12 (1). pp. 261-277. ISSN 2062-5871

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Abstract

Background: Little attention has been given to efficacious treatment and adherence to treatment of compulsive sexual behavior (CSB). Aims: Randomized controlled trial investigated short-term psychodynamic group therapy followed by relapse prevention group (STPGP-RPGT) and pharmacological treatment (PT) for CSB men on sexual compulsivity and adherence. Method: 135 men, 38 (SD 5 9) years old on average, were randomly assigned to 1) STPGP-RPGT; 2) PT; 3) Both. Participants completed measures at baseline, 25th, and 34th week. 57 (42.2%) participants dropped out between baseline and 25th week, and 68 (50.4%) between baseline and 34th week. 94 (69.6%) did not adhere (80% pills taken or attended 75% therapy sessions). Results: A significant interaction effect was found between time and group (F (4, 128) 5 2.62, P 5 0.038, ES 5 0.08), showing who received PT improved less in sexual compulsivity than those who received STPGP-RPGT (t 5 2.41; P 5 0.038; ES 5 0.60) and PT þ STPGP-RPGT (t 5 3.15; P 5 0.007, ES 5 0.74). Adherent participants improved more in sexual compulsivity than non-adherent at the 25th week (t 5 2.82; P 5 0.006, ES 5 0.65) and 34th week (t 5 2.26; P 5 0.027, ES 5 0.55), but there was no interaction effect, F (2, 130) 5 2.88; P 5 0.06; ES 5 0.04). The most reported behavior (masturbation) showed greater risk of non-adherence (72.6%). Discussion and conclusions: Adherent participants improved better than non-adherent. Participants who received psychotherapy improved better than those who received PT. Methodological limitations preclude conclusions on efficacy.

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