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Application of Metathesis Protocols to the Stereocontrolled Synthesis of some Functionalized β-Amino Esters and Azaheterocycles

Semghouli, Anas and Nonn, Melinda and Remete, Attila Márió and Fustero, Santos and Kiss, Loránd (2023) Application of Metathesis Protocols to the Stereocontrolled Synthesis of some Functionalized β-Amino Esters and Azaheterocycles. THE CHEMICAL RECORD, 23. No-e202300279. ISSN 1018–1033

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Abstract

In this account our aim was to give an insight into the application of metathesis protocols (ROM, RCM, RCEYM, CM, RRM) for the synthesis of various azaheterocyclic frameworks. Due to the high biological potential and importance in peptide chemistry and drug design of β-amino acids our intention is to give a highlight on the synthetic procedures and transformation of these class of compounds with the above-mentioned metathesis strategies with emphasis on selectivity, stereocontrol, substrate-directing effect or functional group tolerance.

Item Type: Article
Uncontrolled Keywords: amino acids, azaheterocycles, cyclization, metathesis, stereocontrol
Subjects: Q Science / természettudomány > QD Chemistry / kémia
Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia
Depositing User: Dr Loránd Kiss
Date Deposited: 21 Dec 2023 08:54
Last Modified: 21 Dec 2023 08:54
URI: http://real.mtak.hu/id/eprint/182804

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