Újdonságok az állatorvosi epilepsziában – 2023 : Irodalmi összefoglaló = News in the canine and feline epilepsy 2023

Pákozdy, Ákos (2024) Újdonságok az állatorvosi epilepsziában – 2023 : Irodalmi összefoglaló = News in the canine and feline epilepsy 2023. MAGYAR ÁLLATORVOSOK LAPJA, 146 (3). pp. 145-148. ISSN 0025-004X

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Abstract

A szerző jelen cikkében bemutatja a 2023-ban megjelent nemzetközi tudományos közlemények közül azokat, amelyek ismeretét a legfontosabbnak tartja a praxisban dologozó kollégák részére. Ezek a következő szalagcímekben foglalhatóak össze: autoimmun encephalitist írtak le macskában. Tartós fenobarbitál-kezelés során, macskákon sikeres lehet a naponta egyszeri adagolás is. A fenobarbitál macskákon gyakran okoz hematológiai elváltozásokat, de azok többnyire enyhék, klinikailag nem relevánsak. A fenobarbitál okozta heveny májkárosodás sikerrel kezelhető. Status epilepticus kezelésére vonatkozó, konszenzuson alapuló cikk jelent meg, amely ismerete hasznos lehet a gyakorlatban. Macskák hipertenzív encephalopathiája többnyire javul a vérnyomás rendezésével. | In this „annual mini-review” the most relevant research results in the field of clinical epilepsy in dogs and cats will be described. The author selected and summarised from 2023 several useful findings from the international literature including own works. The following important topics will be presented. Autoimmune encephalitis was described in cats. The first case series has been published ten years ago, but now more detailed description with more cases were published. It seems that the inflammation affects the temporal lobe. Most cats showed acute temporal lobe seizures with orofacial automatism, hypersalivation, facial twiching, gagging. The brain MRI and the CSF analysis were frequently unremarkable but the antibodies against LGI1 (leucine-rich gliome-inactivated 1) was detectable in all cats. Another study showed, that for the treatment of epileptic cats the phenobarbital can be used as once a day therapy, which may be easier for many owners than the usual twice daily treatment. In another study the haematologal f indings were systematically evaluated in cats undergoing phenobarbital therapy. The majority of cats showed neutropenia or other cytopenias, but these changes were usually mild and clinically not relevant. An interesting case report showed how to treat succesfully acute phenobarbital induced liver failure in a dog. Furthermore a consensus statment was published about status epilepticus therapy in dogs and cats. Feline hypertensive encephalopathya and its outcome was evaluated and published.

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