Lee, Hayoon and Lee, Dohee and Park, Jooyoung and Yun, Taesik and Koo, Yoonhoi and Chae, Yeon and Kang, Byeong-Teck and Yang, Mhan-Pyo and Kim, Hakhyun (2023) Heart failure in a cat due to hypertrophic cardiomyopathy phenotype caused by chronic uncontrolled hyperthyroidism. ACTA VETERINARIA HUNGARICA, 71 (2). pp. 96-100. ISSN 0236-6290
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Abstract
A 16-year-old castrated male Persian cat was presented with weight loss, anorexia and dyspnoea. Tachycardia and tachypnoea were observed upon presentation. The cat was previously diagnosed with hyperthyroidism and left ventricular hypertrophy and received methimazole, but was subsequently not followed up and treated appropriately. Thoracic radiography revealed mild pleural effusion, interstitial lung pattern, moderate cardiomegaly and moderate-to-severe dilation of the pulmonary artery and pulmonary vein. On echocardiography, the left ventricular hypertrophy, identified earlier, shoed partial regression. Therefore, the previous myocardial hypertrophy was diagnosed as a hypertrophic cardiomyopathy phenotype related to hyperthyroidism. ST-segment elevation was identified on electrocardiography, and the thyroid profile examination revealed increased total thyroxine and free thyroxine and decreased thyroid-stimulating hormone levels, suggesting myocardial injury and uncontrolled hyperthyroidism, respectively. In addition, normal N-terminal pro-B-type natriuretic peptide and high cardiac troponin I levels were found. Based on these findings, the observed congestive heart failure was considered as a sequel of myocardial injury caused by uncontrolled hyperthyroidism. Clinical signs resolved after intravenous administration of furosemide and butorphanol, oxygen supply and thoracocentesis. Furosemide and pimobendan were additionally administered, and the cat was discharged. This case demonstrates that myocardial damage due to chronic uncontrolled hyperthyroidism may cause heart failure in cats.
| Item Type: | Article |
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| Additional Information: | Funding Agency and Grant Number: Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry (IPET) through Companion Animal Life Cycle Industry Technology Development Program - Ministry of Agriculture, Food and Rural Affairs (MAFRA) [322095-04] Funding text: This work was supported by Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry (IPET) through Companion Animal Life Cycle Industry Technology Development Program, funded by Ministry of Agriculture, Food and Rural Affairs (MAFRA) (322095-04) . |
| Uncontrolled Keywords: | DYSFUNCTION; CARDIOMYOPATHY; TROPONIN-I; feline; NT-proBNP; myocardial damage; THYROID-HORMONE; |
| Subjects: | S Agriculture / mezőgazdaság > SV Veterinary science / állatorvostudomány |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 02 Apr 2024 06:05 |
| Last Modified: | 31 Oct 2024 00:15 |
| URI: | https://real.mtak.hu/id/eprint/191341 |
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