Kocsis, Béla (2023) Hypervirulent Klebsiella pneumoniae: An update on epidemiology, detection and antibiotic resistance. ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA, 70 (4). pp. 278-287. ISSN 1217-8950
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Abstract
Klebsiella pneumoniae is a major human pathogen as it is responsible for various infections. In the past years hypervirulent K. pneumoniae (hvKP) emerged and disseminated worldwide. In this review a summary will be given about epidemiology, detection and antibiotic resistance of hypervirulent K. pneumoniae . A common feature of hypervirulent K. pneumoniae is a combined expression of several virulence factors. A mucoviscosus phenotype, certain capsulare serotypes (e.g.: K1, K2, K28, K47, K63) together with additional genetic markers namely, magA , rmpA or iucABCD, are needed in combinations to achieve the hypervirulent pathotype. Plasmid coded virulence determinants are also detected, that indicates horizontal gene transfer of hypervirulence factors in K. pneumoniae .
| Item Type: | Article |
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| Additional Information: | Funding Agency and Grant Number: Janos Bolyai Scholarship of Hungarian Academy of Sciences [BO/00286/22/5]; Hungarian Academy of Sciences Funding text: B.K. was supported by Janos Bolyai Scholarship (BO/00286/22/5) of the Hungarian Academy of Sciences. |
| Subjects: | Q Science / természettudomány > QR Microbiology / mikrobiológia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 25 Apr 2024 05:42 |
| Last Modified: | 25 Apr 2024 05:42 |
| URI: | https://real.mtak.hu/id/eprint/193135 |
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