Effect of veratrine on the heart receptors and central neurones regulating heart beats in Helix pomatia L.

S.-Rózsa, Katalin (1975) Effect of veratrine on the heart receptors and central neurones regulating heart beats in Helix pomatia L. A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 42. pp. 89-97. ISSN 0365-3005

Preview

Text 91_cut_MTA_TihanyiBiologiaiKutIntEvkonyve_42.pdf Download (6MB) | Preview

Abstract

Studying the peripheral and central effects of the veratrine in Helix heart it was found that: 1. Both the mechano- and chemoreceptors of the heart were excited during intracardial perfusion of veratrine from 10⁻⁶ M concentration. In Helix heart the veratrine cannot be regarded as a specific stimulator of mechanoreceptors. 2. The intensity of potentials registered from heart nerve was decreased as a function of time. Using high concentrations of veratrine (10⁻⁴-10⁻³ M) the response of the receptors became periodic, which can be explained by the oscillation of the receptor membrane. 3. Veratrine had no significant effect on the heart muscle, the obtained effect was the result of reflex influences. 4. The central effect of veratrine was realized on the double-action cells of neuronal network. The veratrine effect at the cellular level depends also on the activity of other inputs in the system. The effects caused by veratrine on the central neurones were always the result of synaptic activation.

Actions (login required)

Edit Item