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Genetics of gambling disorder and related phenotypes: The potential uses of polygenic and multifactorial risk models to enable early detection and improve clinical outcomes

Warrier, Varun and Chamberlain, Samuel R. and Thomas, Shane A. and Bowden-Jones, Henrietta (2024) Genetics of gambling disorder and related phenotypes: The potential uses of polygenic and multifactorial risk models to enable early detection and improve clinical outcomes. JOURNAL OF BEHAVIORAL ADDICTIONS, 13 (1). pp. 16-20. ISSN 2062-5871

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Abstract

Gambling Disorder (GD) is an impactful behavioural addiction for which there appear to be under- pinning genetic contributors. Twin studies show significant GD heritability results and intergenera- tional transmission show high rates of transmission. Recent developments in polygenic and multifactorial risk prediction modelling provide promising opportunities to enable early identification and intervention for at risk individuals. People with GD often have significant delays in diagnosis and subsequent help-seeking that can compromise their recovery. In this paper we advocate for more research into the utility of polygenic and multifactorial risk modelling in GD research and treatment programs and rigorous evaluation of its costs and benefits.

Item Type: Article
Uncontrolled Keywords: work addiction, problematic mobile phone use, driving, anxiety, worry, rumination
Subjects: B Philosophy. Psychology. Religion / filozófia, pszichológia, vallás > BF Psychology / lélektan
H Social Sciences / társadalomtudományok > HM Sociology / társadalomkutatás
SWORD Depositor: MTMT SWORD
Depositing User: Zsolt Baráth
Date Deposited: 21 May 2024 13:53
Last Modified: 17 Jan 2025 09:42
URI: https://real.mtak.hu/id/eprint/195349

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