Effect of Actinomycin-D on the monoamine content of the central nervous system in the fresh-water mussel Anodonta cygnea L. as revealed by fluorescence histochemistry

Elekes, Károly and Zs.-Nagy, Imre (1972) Effect of Actinomycin-D on the monoamine content of the central nervous system in the fresh-water mussel Anodonta cygnea L. as revealed by fluorescence histochemistry. A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 39. pp. 3-11. ISSN 0365-3005

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Abstract

The effect of AD on the monoamine content of the central nervous system of Anodonta cygnea l. was investigated by fluorescence histochemical method. Eight hours after treatment the 5HT and DA content of the nerve cells strongly decreased. At the same time, the intensity of the fluorescence of the neuropile decreased only in some places. The cells showing green fluorescence appeared again already 24 hours following treatment, while the restoration of 5HT synthesis needed more time (48 hours). The reconciliation and differences of the results are discussed by the authors in relation to t heir former electron microscopic data.

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