Fibrinogen to albumin ratio’s prognostic value in ischemic stroke patients who underwent mechanical thrombectomy

Ozdogru, Derya and Uysal, Onur Kadir and Erdem, Miray and Soker, Elif Banu and Ozturk, Ilker and Avci, Akkan and Arlier, Zulfikar (2024) Fibrinogen to albumin ratio’s prognostic value in ischemic stroke patients who underwent mechanical thrombectomy. IDEGGYOGYASZATI SZEMLE / CLINICAL NEUROSCIENCE, 77 (5-6). pp. 167-176. ISSN 0019-1442

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Abstract

Background and purpose – Fibrinogen to albumin ratio (FAR) is thought to have a predictive effect in diseases such as cancer and myocardial infarction. We aimed to elucidate the prognostic value of FAR in ischemic stroke patients who underwent mechanical thrombectomy. Methods – A total of 103 patients hospitalized for acute stroke who underwent mechanical thrombectomy within 6 hours of symptoms’ outset have been analyzed retrospectively. Stroke severity was interpreted via the National Institutes of Health Stroke Scale (NIHSS) score during the neurological examination. Recanalization success after mechanical thrombectomy was evaluated with the TICI score (Thrombolysis in Cerebral Infarction scale), and 2b – 3 patients were recorded as those with recanalization. The patients’ modified Rankin scale (mRS) at discharge and at the end of the third month were recorded. Results – Statistically significant differences were observed in age, admission blood glucose, glomerular filtration rate and FAR according to the mRS scores of the patients in the third month (p<0.05). Significant variables in the risk factor analysis were re-evaluated in the multivariate model. The best model was determined using the backward Wald method in the multivariate model,and it was determined that differences in age, admission blood glucose, and FAR were significant. Conclusion – FAR can be used as a novel, effective, economical, and practical biomarker in patient with acute ischemic stroke who underwent mechanical thrombectomy.

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