Nyisztratova, Szerafina N. and Pécsi, Tibor (1966) Analysis of the action of some cholinergic compounds on the heart of fresh-water mussel (Anodonta sp.). A Magyar Tudományos Akadémia Tihanyi Biológiai Kutatóintézetének évkönyve, 33. pp. 111-123. ISSN 0365-3005
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Abstract
The effect of various cholinergic compounds on the in situ heart of Anodonta cygnea and also on the isolated heart of this mollusc was studied. It was found that nicotine, trimethylammonium chloride and tetramethylammonium iodide have an effect similar to ACh: in low concentrations they increase the amplitude of contractions, in high concentrations they increase the tone and diminish the amplitude completely. In the case of repeated application of these compounds “desensitization” sets in both to themselves and also to ACh injected from outside. Mytolon, tetraethylammonium iodide and arpenal increase the amplitude of contractions of the heart and work as ACh antagonists. After a treatment of the heart with these compounds, ACh or the stimulation of the visceral ganglion produce a stimulatory effect in consequence of released macroerg compound (or compounds). Mesphenal also diminished the effect of ACh but did not change the strength of contractions of the ventricle. M-cholinomimetic arecoline produced a slight increase in amplitude but did no influence the effect of ACh. The pecularities of ACh receptors in the heart of molluscs are discussed in comparison with cholinoreceptors of vertebrates.
Item Type: | Article |
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Subjects: | Q Science / természettudomány > QL Zoology / állattan |
Depositing User: | Edina Fejős |
Date Deposited: | 15 Jun 2024 11:04 |
Last Modified: | 15 Jun 2024 11:04 |
URI: | https://real.mtak.hu/id/eprint/197470 |
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