Reduction of intracellular oxidative stress with a copper-incorporated layered double hydroxide

Szerlauth, Adél and Madácsy, Tamara and Samu, Gergely Ferenc and Biró, Péter and Erdélyi, Péter and Varga, Gábor and Xu Ping, Zhi and Maléth, József and Szilágyi, István (2024) Reduction of intracellular oxidative stress with a copper-incorporated layered double hydroxide. CHEMICAL COMMUNICATIONS (10). ISSN 1359-7345

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Abstract

Biocompatible Cu(II)-doped layered double hydroxide (CMA) nanoparticles were developed to combat reactive oxygen species. The 2-dimensional nanozymes showed both superoxide dismutase- and catalase-like activities in chemical assays, while proving as efficient antioxidants in the reduction of intracellular oxidative stress. The results indicate the great promise of CMA in antioxidant therapies.

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