Surgical treatment of Cushing's disease caused by adrenocortical hyperplasia: experiences with bilateral adrenalectomy

László, F. A. and Durszt, F. and Julesz, J. and Petri, Gábor (1976) Surgical treatment of Cushing's disease caused by adrenocortical hyperplasia: experiences with bilateral adrenalectomy. ACTA MEDICA ACADEMIAE SCIENTIARIUM HUNGARICAE, 33 (1). pp. 63-80. ISSN 0001-5989

Preview

Text Petri_03_ActaMedica_33.pdf - Published Version Download (6MB) | Preview

Abstract

Experience with the surgical treatm ent of hypercorticism caused by bilateral adrenocortical hyperplasia in 16 patients is discussed. The treatm ent of choice is bilateral total adrenalectomy. Following subtotal adrenalectomy recurrence occurred in three of six patients; a third operation was needed in two cases, while permanent hypadrenia developed in the third. There was no operative mortality. One patient died 9 years after surgery, but the death was not related to the original disease. The clinical symptoms of hypercorticism subsided in every totally adrenalectomized patient. Indication and contraindication of adrenalectomy, the surgical method, and the prob lems of pre- and postoperative treatm ent are discussed.

Actions (login required)

Edit Item