Cellular immune functions after heart operations

Petri, Ildikó and Kaiser, G. and Gaál, T. and Kovács, G. and Petri, Gábor (1981) Cellular immune functions after heart operations. ACTA CHIRURGICA ACADEMIAE SCIENTIARUM HUNGARICAE, 22 (1-2). pp. 29-36. ISSN 0001-5431

Preview

Text Petri_10_ActaChirurgica_22.pdf - Published Version Download (3MB) | Preview

Abstract

Eight patients were observed by mitogen stimulation and E-rosetting after heart operations with and without cardiopulmonary bypass. The first sample of blood was taken before surgery, the second on the afternoon of the same day and for a week daily examinations were carried out. A depression of mitogen- stim ulated lymphocyte transformation was observed, parallel with a simultaneous T cell depression and a general decrease in the total WBC count. The lowest values were foimd during the first three days after both open and closed heart operations. After open heart surgery it took a longer time until the values had returned to normal. I n two other cases the lymphocytes were examined for suppressor activity. The suppressive effect exerted on the response to mitogenic and allogeneic stim ulation was not uniform. Suppressor activity was more affected by surgery than the helper effect in these two cases.

Actions (login required)

Edit Item