Microfluidic Cuvette for Near-Infrared Spectroscopy

Szabó, Zoltán and Pankász, Kitti and Bozorádi, János Márk and Hakkel, Orsolya and Bella, Szabolcs and Fabinyi, Bianka and Meucci, Sandro and Fürjes, Péter (2024) Microfluidic Cuvette for Near-Infrared Spectroscopy. PROCEEDINGS, 97 (1). No. 209. ISSN 2504-3900

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Abstract

We intend to develop an in situ near-infrared spectroscopic solution for monitoring the nutrient composition (e.g., lactate concentration) in microfluidic channels of organ-on-chip devices. In this work, the effects of the geometry, surface quality, and architecture of the micro-volume cuvettes were characterized and optimized considering the signal-to-noise ratio and sensitivity of the proposed spectroscopic method in case of aqueous solutions. The applicability of the micro-volume near-infrared spectroscopy method using this specially designed microfluidic cuvette was proven.

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