Lactate concentration increase in female college students with idiopathic scoliosis: A cross-sectional study

Prastowo, Nawanto Agung and Tjhin, Maria Karen and Santosa, Mariani and Tanjung, Julia Rahadian and Haryono, Ignatio Rika (2025) Lactate concentration increase in female college students with idiopathic scoliosis: A cross-sectional study. PHYSIOLOGY INTERNATIONAL, 112 (1). pp. 33-39. ISSN 2498-602X

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Abstract

Purpose: Scoliosis may create muscle imbalance and disturb muscle metabolism. However, no studies have examined muscle cell metabolism in scoliosis. This study evaluates lactate concentration in female college students with scoliosis. Methods: One hundred fifty female college students followed this cross-sectional analytic study. Inclusion and exclusion criteria were applied. Scoliosis was measured using a scoliometer. A scoliometer reading of 58 was considered scoliosis. Lactate concentration was measured using a lactate analyzer, and a lactate value above 2 mg dL1 was denoted as ‘elevated.’ Anova and post hoc tests were used to analyze differences in the variables between scoliosis and normal subgroups. The results were significant if P < 0.05. Results: One hundred participants (66.7%) had a spinal curve angle of more than 58. Only weight in thoracic scoliosis was lower than normal (P 5 0.022). Lactate was significantly higher than normal in all scoliosis subtypes (P < 0.001). Lactate in both types was considerably higher than thoracic and lumbar scoliosis (P 5 0.04 and 0.03, respectively). Conclusion: Lactate concentration increased in female students with scoliosis.

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