Vizsnyiczai, Gaszton and Kubacková, Jana and Iványi, Tamás Gergely and Slabý, Cyril and Horváth, Denis and Hovan, Andrej and Strejčková, Alena and Tomori, Zoltán and Kelemen, Lóránd and Bánó, Gregor (2024) 3D-printed ultra-small Brownian viscometers. SCIENTIFIC REPORTS, 14. No. 13964. ISSN 2045-2322
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Abstract
Measuring viscosity in volumes smaller than a microliter is a challenging endeavor. A new type of microscopic viscometers is presented to assess the viscosity of Newtonian liquids. Micron-sized flexible polymer cantilevers are created by two-photon polymerization direct laser writing. Because of the low stiffness and high elasticity of the polymer material the microcantilevers exhibit pronounced Brownian motion when submerged in a liquid medium. By imaging the cantilever’s spherically shaped end, these fluctuations can be tracked with high accuracy. The hydrodynamic resistance of the microviscometer is determined by fitting the power spectral density of the measured fluctuations with a theoretical frequency dependence. Validation measurements in water-glycerol mixtures with known viscosities reveal excellent linearity of the hydrodynamic resistance to viscosity, allowing for a simple linear calibration. The stand-alone viscometer structures have a characteristic size of a few tens of microns and only require a very basic external instrumentation in the form of microscopic imaging at moderate framerates (~ 100 fps). Thus, our results point to a practical and simple to use ultra-low volume viscometer that can be integrated into lab-on-a-chip devices.
| Item Type: | Article |
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| Additional Information: | Funding Agency and Grant Number: Slovak Research and Development Agency [APVV-21-0333]; Ministry of Education, Science, Research and Sports of the Slovak Republic [VEGA 2/0101/22]; ERDF [313011V455]; Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences [BO/00290/21/11]; New National Excellence Program of the Ministry for Innovation and Technology from the source of The National Research, Development and Innovation Fund [UNKP-23-5-SZTE-717]; National Research, Development and Innovation Office, Hungary [FK 138520]; Hungarian Research Network [SA-75/2021] Funding text: This work was supported by the Slovak Research and Development Agency, grant APVV-21-0333, and by the grant agency of the Ministry of Education, Science, Research and Sports of the Slovak Republic, grant VEGA 2/0101/22. This publication is the result of the implementation of the projects OPENMED (Open Scientific Community for Modern Interdisciplinary Research in Medicine) ITMS2014+: 313011V455 from the Operational Program Integrated Infrastructure funded by the ERDF. GV was supported by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (BO/00290/21/11) and by the & Uacute;NKP-23-5-SZTE-717 New National Excellence Program of the Ministry for Innovation and Technology from the source of The National Research, Development and Innovation Fund. This work was supported by the National Research, Development and Innovation Office, Hungary, under grant number FK 138520 and by the Hungarian Research Network under grant number SA-75/2021. |
| Uncontrolled Keywords: | Viscometer, Brownian fuctuations, Power spectral density, Two-photon polymerization, Viscoelastic polymer nanowire |
| Subjects: | Q Science / természettudomány > QH Natural history / természetrajz > QH301 Biology / biológia > QH3020 Biophysics / biofizika |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 21 Apr 2025 18:42 |
| Last Modified: | 21 Apr 2025 18:42 |
| URI: | https://real.mtak.hu/id/eprint/217958 |
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