Szűcs, Anna and Barcs, G. and Winkler, Gábor and Soós, Z. and Folyovich, András and Kamondi, Anita (2014) Anti glutamate-decarboxylase antibodies: A liaison between localisation related epilepsy, stiff-person syndrome and type-1 diabetes mellitus. IDEGGYÓGYÁSZATI SZEMLE / CLINICAL NEUROSCIENCE, 67 (7-8). pp. 269-271. ISSN 0019-1442
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anti_glutamat_dekarboxilaz_antitestek_kapcsolat_a_lokalizaciofuggo_epilepszia_a_stiff_person_szindroma_es_az_1_es_tipusu_diabetes_mellitus_kozott_12589_u.pdf Download (103kB) | Preview |
Abstract
We present two patients with partial epilepsy, type-1 diabetes and stiff person syndrome associated with high serum autoantibody levels to glutamate-decarboxylase (anti-GAD). Both patients were or have suffered from additional autoimmune conditions. The presence of stiff person syndrome and elevated anti-GAD levels have to make clinicians look for additional autoimmune conditions including type-1 diabetes. On the other hand, the co-morbidity of partial epilepsy with autoimmune conditions in patients with elevated serum anti-GAD suggests an autoimmune mechanism of partial epilepsy in these cases.
| Item Type: | Article |
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| Uncontrolled Keywords: | stiff man syndrome; nuclear magnetic resonance imaging; Middle Aged; insulin dependent diabetes mellitus; human; FOCAL EPILEPSY; Female; Electromyography; Comorbidity; case report; ARTICLE; Aged; Adult; pregabalin; methylprednisolone; glutamate decarboxylase antibody; DIAZEPAM; clonazepam; baclofen; Stiff person's; Autoimmune epilepsy; Anti-GAD |
| Subjects: | R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 14 Jul 2015 05:30 |
| Last Modified: | 12 Jan 2016 14:45 |
| URI: | http://real.mtak.hu/id/eprint/25325 |
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