Metasztatikus csontdaganatos esetek a római kori Pannóniából. [Skeletal metastases from the Roman Period of Pannonia.]

Hajdu, Tamás and Merczi, Mónika and Marcsik, Antónia and Bernert, Zsolt and Józsa, László and Buczkó, Krisztina and Zádori, Péter and Lelovics, Zsuzsanna and Vandulek, Csaba and Biró, Gergely and Molnár, Erika (2014) Metasztatikus csontdaganatos esetek a római kori Pannóniából. [Skeletal metastases from the Roman Period of Pannonia.]. ANTHROPOLOGIAI KÖZLEMÉNYEK, 55. pp. 27-44. ISSN 0003-5440

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Abstract

According to paleopathological literature, tumors have a great antiquity. The prevalence of tumor metastases in historical populations might have differed from that in modern humans, because of substantial differences in environmental factors, life expectancy, and the availability of treatment. This study presents two probable cases of skeletal metastatic carcinoma from the Roman Period (1st – 5 th century AD) in Hungary, showing the development of bony metastasis of cancer without chemo - and radiotherapy. During the paleopathological analysis macroscopic investigation, radiological, stereo - and scanning electron microscopic analyses were applied. In one case the mixed nature and the localization of the lesions, as well as the sex and age of the individual suggest breast cancer for the primary focus. In the other case based on the mostly osteoblastic nature and the localization of the lesions, more over on the sex and age of the individuals, the most probable diagnostic option is prostate carcinoma with skeletal metastases. In view of the scarcity of cancer metastases, that have been diagnosed in archaeological specimens in general, identification of all examples of cancer in antiquity represents an important contribution both to paleopathology and to modern medicine.

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