Tukacs, József M. and Fridrich, Bálint and Dibó, Gábor and Székely, Edit and Mika, László T. (2015) Direct asymmetric reduction of levulinic acid to gamma-valerolactone: synthesis of a chiral platform molecule. Green Chemistry, 17. pp. 5189-5195. ISSN 1463-9262
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Abstract
Levulinic acid was directly converted to optically active (S)-gamma-valerolactone, a proposed biomass-based chiral platform molecule. By using a SEGPHOS ligand-modified ruthenium catalyst in methanol as a co-solvent, eventually, 100% chemoselectivity, and 82% enantioselectivity were achieved. The effect of the catalyst composition and reaction parameters on the activity and selectivity was investigated in detail. The conversion of a “real” biomass derived levulinic acid to optically active GVL without decreasing the enantioselectivity was also demonstrated.
| Item Type: | Article |
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| Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
| Depositing User: | Dr. Laszlo T, Mika |
| Date Deposited: | 10 Sep 2015 14:10 |
| Last Modified: | 06 Jun 2016 18:17 |
| URI: | http://real.mtak.hu/id/eprint/26258 |
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