Kiss, Loránd and Kardos, Márton and Forró, Enikő and Fülöp, Ferenc (2015) Stereocontrolled One-Step Synthesis of Difunctionalised Cispentacin Derivatives through Ring-Opening Metathesis of Norbornene β-Amino Acids. European Journal of Organic Chemistry, 2015 (6). pp. 1283-1289. ISSN 1434-193X
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Abstract
Through the ring-opening metathesis of norbornene or oxanorbornene β-amino acids with ethylene in the presence of certain Ru catalysts, a facile and convenient stereocontrolled one-step method was devised for the preparation of divinylated cispentacins and oxacyclic cispentacin stereoisomers with four chiral centres. The products are interesting scaffolds for peptide chemistry and for the synthesis of novel functionalised materials through olefinic bond transformations. The ring-opening metathesis proceeds without affecting the chiral centres of the starting molecules, so that their stereochemistry was conserved and determines the configuration of the chiral centres in the products.
Item Type: | Article |
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Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
Depositing User: | Dr Loránd Kiss |
Date Deposited: | 12 Sep 2015 18:22 |
Last Modified: | 13 Sep 2015 23:19 |
URI: | http://real.mtak.hu/id/eprint/26341 |
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