Nonn, Melinda and Kiss, Loránd and Hanninen, Mikko and Fülöp, Ferenc (2015) An insight into the synthesis of novel arylsubstituted alicyclic b-amino acid derivatives through substrate-directed palladium-catalysed regio- and stereoselective cross-coupling. RSC Advances, 5. pp. 13628-13634.
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Abstract
Novel aryl-substituted alicyclic b-amino acid derivatives were synthesized through substrate-determined palladium-catalysed cross-coupling of aryl iodides with five- or six-membered cycloalkene b-amino esters. The arylations were investigated with different catalysts, solvents, bases and aryl halides, and with some cyclohexene 2-aminocarboxylate isomers. The stereochemistry and the position of the ring olefinic bond of the starting 2-aminocycloalkanecarboxylate influenced the coupling reaction, and predetermined the structure of the arylated product.
Item Type: | Article |
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Subjects: | Q Science / természettudomány > QD Chemistry / kémia Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
Depositing User: | Dr Loránd Kiss |
Date Deposited: | 12 Sep 2015 18:25 |
Last Modified: | 12 Sep 2015 18:25 |
URI: | http://real.mtak.hu/id/eprint/26342 |
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