Serum soluble E-selectin and NT-proBNP levels additively predict mortality in diabetic patients with chronic heart failure.

Czúcz, Judit and Cervenak, László and Förhécz, Zsolt and Gombos, Tímea and Pozsonyi, Zoltán and Kunde, Jan and Karádi, István and Jánoskuti, Lívia and Prohászka, Zoltán (2011) Serum soluble E-selectin and NT-proBNP levels additively predict mortality in diabetic patients with chronic heart failure. Clinical research in cardiology : official journal of the German Cardiac Society, 100 (7). pp. 587-594. ISSN 1861-0692

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Abstract

This study demonstrated a weak correlation of sE-selectin level with inflammatory markers and prediction of short-term mortality in diabetic CHF patients. Elevated serum sE-selectin levels and concomitantly increased NT-proBNP concentrations have additive predictive power in CHF. This suggests that parallel activation of various pathophysiological pathways confers increased risk of adverse outcome in CHF.

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