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Genetic analysis of the RELN gene: gender specific association with Alzheimer’s disease

Fehér, Ágnes and Juhász, Anna and Pákáski, Magdolna and Kálmán, János and Janka, Zoltán (2015) Genetic analysis of the RELN gene: gender specific association with Alzheimer’s disease. Psychiatry Research, 230 (2). pp. 716-718. ISSN 0165-1781

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Abstract

Association between genetic variants of the reelin (RELN) gene and the risk for developing Alzheimer’s disease (AD) was examined in a sample of 432 patients and 308 controls. Single marker and haplotype analyses revealed that the strongly linked rs528528 and rs607755 polymorphisms are associated with AD risk in a gender specific manner. Among men, but not in women the rs528528 T/T and rs607755 A/A genotypes were significantly associated with the susceptibility to AD.

Item Type: Article
Subjects: R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában
Depositing User: Dr Ágnes Fehér
Date Deposited: 25 Sep 2015 23:24
Last Modified: 30 Sep 2016 23:15
URI: http://real.mtak.hu/id/eprint/28116

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