CIDRE: an illumination-correction method for optical microscopy

Smith, Kevin and Li, Yunpeng and Piccinini, Filippo and Csucs, Gabor and Balazs, Csaba and Horváth, Péter (2015) CIDRE: an illumination-correction method for optical microscopy. NATURE METHODS, 12 (5). pp. 404-406. ISSN 1548-7091

Text SmithNatureMethods.pdf Restricted to Repository staff only Download (590kB) | Request a copy

Abstract

Uneven illumination affects every image acquired by a microscope. It is often overlooked, but it can introduce considerable bias to image measurements. The most reliable correction methods require special reference images, and retrospective alternatives do not fully model the correction process. Our approach overcomes these issues for most optical microscopy applications without the need for reference images.

Actions (login required)

Edit Item