Nonn, Melinda and Kiss, Loránd and Sillanpää, Reijo and Fülöp, Ferenc (2012) Synthesis of highly functionalized β-aminocyclopentanecarboxylate stereoisomers by reductive ring opening reaction of isoxazolines. Beilstein Journal of Organic Chemistry, 8. pp. 100-106. ISSN ESSN: 1860-5397
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Abstract
A rapid and simple procedure was devised for the synthesis of multifunctionalized cyclic β-amino esters and γ-amino alcohols via the 1,3-dipolar cycloaddition of nitrile oxides to β-aminocyclopentenecarboxylates. The opening of the isoxazoline reductive ring to the corresponding highly functionalized 2-aminocyclopentanecarboxylates occurred stereoselectively with good yields.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
| Depositing User: | Dr Loránd Kiss |
| Date Deposited: | 30 Dec 2015 19:49 |
| Last Modified: | 30 Dec 2015 19:49 |
| URI: | http://real.mtak.hu/id/eprint/31585 |
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