Effect of topical anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats’ tooth surface

Bachtiar, Endang W. and Afdhal, Anggraeni and Meidyawati, Ratna and Soejoedono, Retno D. and Poerwaningsih, Erni (2016) Effect of topical anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats’ tooth surface. Acta Microbiologica et Immunologica Hungarica, 63 (2). pp. 159-169. ISSN 1217-8950

Preview

Text 030.63.2016.2.2.pdf Download (325kB) | Preview

Abstract

This study aims to evaluate the effect of anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats’ tooth surface. Sprague Dawley rats were exposed intra-orally with S. mutans Xc and were fed a caries-inducing diet 2000. The 24 rats were divided into four groups: group A had their teeth coated with IgY gel; group B received sterilized water as a control; group C had their teeth coated with IgY gel starting on the 29^th day; and group D had their teeth coated with a gel without IgY. Plaque samples were swabbed from the anterior teeth for S. mutans colony quantification, and saliva was collected to measure immunoreactivity by enzyme-linked immunosorbent assay. The results indicated that the quantity of S. mutans in rats treated with IgY gel showed significant difference compared with the controls. After coating with IgY anti-S. mutans gel, the mean immunoreactivity in rat saliva was higher than that of the no treatment group. In conclusion, topical application with anti-S. mutans IgY gel reduced the quantity of S. mutans on the tooth surface.

Actions (login required)

Edit Item