Advanced Pediatric Inoperable Thymus Carcinoma (Type C Thymoma): Case Report on a Novel Therapeutic Approach

Kertész, Gabriella P. and Hauser, Péter and Varga, Péter and Dabasi, Gabriella and Schuler, Dezső and Garami, Miklós (2007) Advanced Pediatric Inoperable Thymus Carcinoma (Type C Thymoma): Case Report on a Novel Therapeutic Approach. Journal of Pediatric Hematology/Oncology, 29 (11). pp. 774-775. ISSN 1077-4114 (print), 1536-3678 (online)

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Abstract

Although there has been considerable advancement in treatment techniques but still there are some illnesses that continue to exhibit a rather poor curability, such as thymoma. This report highlights the benefit of octreotide and prednisolone therapy in a 15-year-old girl, who was diagnosed with inoperable thymus carcinoma, with chemotherapy and radiotherapy being the last resort. The detection of type 2 somatostatin receptors on the surface of the tumor justified the introduction of treatment with somatostatin analog and prednisolone. Fortunately, after 6 months of this treatment, the tumor showed partial regression. However, 2 months later, somatostatin receptor negative metastases appeared; therefore, a switch over to imatinib became essential, because the tumor was CD-117 positive. Despite the therapy change, the patient's condition deteriorated owing to tumor progression.

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