Antioxidant properties of Myrtilli folium, Phaseoli fructus sine seminibus and drug mixture extracts

Then, M. and Szentmihályi, K. and Gere, A. and Jasztrab, Sz. and Szőke, É. (2005) Antioxidant properties of Myrtilli folium, Phaseoli fructus sine seminibus and drug mixture extracts. Acta Alimentaria, 34 (2). pp. 169-176. ISSN 0139-3006

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Abstract

In vitro investigations for the antioxidant and free radical scavenging activity of Myrtilli folium-, Phaseoli fructus sine seminibus- and a drug mixture (Equiseti herba, Myrtilli folium, Phaseoli fructus sine seminibus, Urticae folium) extracts showed antioxidant (LPO inhibitory and chain-breaking antioxidant) activity and free radical (superoxide anion and hydroxyl radical) scavenging effect. The extracts inhibited lipid peroxidation induced enzymatically by adding NADPH and non-enzymatically by adding Fe2+ in brain microsomes and in brain homogenates, respectively. The extracts reduced the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH), which showed chain-breaking antioxidant activity. The extracts scavenged superoxide radicals (O2-·) by inhibiting the reduction of nitro blue tetrazolium evoked by phenazine methosulphate. In addition, the extracts inhibited Fenton-reagent (Fe2+ and H2O2) induced deoxyribose degradation, therefore, it was concluded that the extracts have hydroxyl radical (OH·) scavenging property.

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