Teratogenicity testing of BI 58 EC (38% dimethoate) in chicken embryos with special respect to degradation of the active ingredient

Várnagy, L. and Budai, P. and Molnár, Erzsébet and Füzesi, I. and Fáncsi, T. (2001) Teratogenicity testing of BI 58 EC (38% dimethoate) in chicken embryos with special respect to degradation of the active ingredient. Acta Veterinaria Hungarica, 49 (3). pp. 355-361. ISSN 0236-6290

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Abstract

The insecticide formulation BI 58 EC was tested for teratogenicity in chicken embryos, with particular reference to degradation of the active ingredient (dimethoate) after the treatment of embryonated eggs. The pesticide was diluted in water to a concentration level of 0.8%, and the emulsion was injected into the air space in a volume of 0.1 ml/egg, or hen’s eggs were treated by the immersion technique. Residues of dimethoate were measured in the samples on days 13, 15 and 19 of the incubation of chicken embryos, and morphological examinations were performed simultaneously. Analytical chemistry data indicated a slower degradation of dimethoate in embryos after the immersion of eggs, and cyllosis was remarkable in this group among the sporadic developmental anomalies. The liver tissues ofboth treated groups exhibited severe fatty infiltration.

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