Interactions between naturally occurring antifungal agents

Tóth, Viktória and Szilágyi, Melinda and Anton, Fruzsina and Leiter, Éva and Pócsi, I. and Emri, T. (2013) Interactions between naturally occurring antifungal agents. Acta Biologica Hungarica, 64 (4). pp. 510-512. ISSN 0236-5383

Text abiol.64.2013.4.11.pdf Restricted to Repository staff only until 31 December 2033. Download (120kB)

Abstract

Pairwise interactions between four antifungal compounds were studied. The β-1,3-glucan synthase inhibitor echinocandin B (ECB) showed synergistic effect with the cell wall hydrolase ChiB chitinase and EngA β-1,3-glucanase on Saccharomyces cerevisiae, Candida albicans, Aspergillus rugulosus and A. fumigatus. The antifungal protein of Penicillium chrysogenum (PAF) did not influence the antifungal activity of ChiB or EngA, but showed antagonistic effect with ECB on A. nidulans, A. rugulosus and A. fumigatus. PAF had no significant effect on the growth of the tested yeasts as it was expected and did not influence significantly the antifungal activity of ECB, ChiB or EngA against yeasts.

Actions (login required)

Edit Item