Syphilis and HIV coinfection — Hungarian Sexually Transmitted Infection Centre Experience between 2005 and 2013

Pónyai, Katinka and Ostorházi, Eszter and Mihalik, Noémi and Rozgonyi, Ferenc and Kárpáti, Sarolta and Marschalkó, Márta (2013) Syphilis and HIV coinfection — Hungarian Sexually Transmitted Infection Centre Experience between 2005 and 2013. Acta Microbiologica et Immunologica Hungarica, 60 (3). pp. 247-249. ISSN 1217-8950

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Abstract

Background: STIs like HIV and syphilis are acquired as comorbidities by high risk populations and may influence their original course and prognosis. Methods: Be- tween January of 2005 and 2013 data of syphilis and HIV patients were collected at the Department of Dermatology of Semmelweis University, Budapest . Diagnostic proce- dures included clinical analysis and screening of serum samples for Treponema pallidum and HIV antibodies. Results: A total of 1,401 new syphilitic and 338 new HIV infections were diagnosed. In syphilis patients 86.58% had monoinfection, 7.92% already had an HIV infection and 5.5% had acquired syphilis and HIV infection simultaneously, so 22.78% of the new HIV patients acquired the infection with syphi - lis together. Male gender, MSM (men who had sex with men) orientation and positive past venerological history were dominant in all groups. Most patients were diagnosed in a latent infectious stage based on the result of a serological check-up. Secondary stage and neurosyphilis were more common in coinfections. Conclusion: (i) male gen - der, MSM orientation, and positive venerological history are risk factors for acquiring new STIs, (ii) clinical course were different in HIV infected patients, (iii) but their timely and regular check-ups resulted in earlier diagnosis of syphilis, suggesting the necessity for frequent screening.

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