Palladium- and/or Copper-Catalyzed Cross-Coupling Reactions of Paramagnetic Vinyl Bromides and Iodides

Úr, Györgyi and Gulyás Fekete, Gergely and Jekö, József and Hideg, Kálmán and Kálai, Tamás (2017) Palladium- and/or Copper-Catalyzed Cross-Coupling Reactions of Paramagnetic Vinyl Bromides and Iodides. Synthesis-Stuttgart. ISSN 0039-7881 (In Press)

Text ss-2017-n0058-op.pdf Restricted to Registered users only Download (219kB)

Abstract

A series of new 3-substituted-4-iodo-(2,2,5,5-tetramethyl- 2,5-dihydro-1H-pyrrol-1-yl)oxidanyl compounds is synthesized to achieve NH2- and SH-specific spin labels. The new vinyl iodides are tested in Sonogashira and Buchwald–Hartwig cross-coupling reactions to produce a paramagnetic β-amino acid ester, pyrroline nitroxide-condensed heterocycles, including a paramagnetic α,α′-dipyridyl ligand and a spin-labeled sulfonamide.

Actions (login required)

Edit Item