MisPred: a resource for identification of erroneous protein sequences in public databases

Nagy, Alinda and Patthy, László (2013) MisPred: a resource for identification of erroneous protein sequences in public databases. Database, 2013. pp. 1-7. ISSN 1758-0463


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Correct prediction of the structure of protein-coding genes of higher eukaryotes is still a difficult task; therefore, public databases are heavily contaminated with mispredicted sequences. The high rate of misprediction has serious consequences because it significantly affects the conclusions that may be drawn from genome-scale sequence analyses of eukaryotic genomes. Here we present the MisPred database and computational pipeline that provide efficient means for the identification of erroneous sequences in public databases. The MisPred database contains a collection of abnormal, incomplete and mispredicted protein sequences from 19 metazoan species identified as erroneous by MisPred quality control tools in the UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, NCBI/RefSeq and EnsEMBL databases. Major releases of the database are automatically generated and updated regularly. The database ( is easily accessible through a simple web interface coupled to a powerful query engine and a standard web service. The content is completely or partially downloadable in a variety of formats.

Item Type: Article
Subjects: Q Science / természettudomány > QP Physiology / élettan
Depositing User: Dr. Alinda Nagy
Date Deposited: 29 Aug 2013 09:35
Last Modified: 15 May 2023 11:54

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