Ivanišević-Milovanović, Olivera K. and Demajo, M. and Petrović, V. and Cvijić, Gordana (2003) Total monoamine oxidase activity in the hypothalamus, ovary and uterus of rats with an extreme number of ovarian corpora lutea. Acta Physiologica Hungarica, 90 (4). pp. 319-325. ISSN 0231-424X
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Abstract
The activity of total monoamine oxidase (MAO) in the rat ovary and uterus fluctuates significantly under various physiological conditions. We analyzed total MAO activity in the hypothalamus, uterus and ovary in adult rats, having an extreme number of corpora lutea (hyperluteinized ovaries) resulting from the mechanical lesions in the posterior hypothalamic region of neonatal rats. Total MAO activity in the hypothalamus (30.21±1.53 pmol/mg tissue/min) and uterus (3.16±0.61 pmol/mg tissue/min) of rats with hyperluteinized ovaries did not show a significant difference as compared to that of intact controls (31.09±1.72 and 2.90 ± 0.40 pmol/mg tissue/min, respectively). In contrast, in the ovaries of hyperluteinized rats, total MAO activity (21.16±1.70 pmol/mg tissue/min) was significantly higher (p<0.01) when compared to that of intact controls (13.61±1.30 pmol/mg tissue/min). The increased MAO activity in the hyperluteinized ovaries may be attributed to the increased number of transformed and accumulated corpora lutea as a consequence of diminished luteolysis.
Item Type: | Article |
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Subjects: | R Medicine / orvostudomány > R1 Medicine (General) / orvostudomány általában |
Depositing User: | xFruzsina xPataki |
Date Deposited: | 01 Nov 2017 08:22 |
Last Modified: | 31 Dec 2023 00:15 |
URI: | http://real.mtak.hu/id/eprint/63962 |
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