Second messengers of octopamine receptors in the snail Lymnaea

Pitt, Samantha and Vehovszky, Ágnes and Szabó, Henriette and Elliott, C. J. H. (2004) Second messengers of octopamine receptors in the snail Lymnaea. Acta Biologica Hungarica, 55 (1-4). pp. 177-183. ISSN 0236-5383

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We describe octopamine responses of 3 large buccal neurons of Lymnaea and test the hypothesis that these are cAMP-dependent. The B1 neuron is excited by octopamine and the depolarisation is significantly enlarged (P<0.05) by application of the blocker of cAMP breakdown, 3-isobutyl-1-methylxanthine (IBMX). The B1 neuron is also depolarised by forskolin, an activator of adenylyl cyclase. The B2 and B3 neurons are inhibited by octopamine, and the response is not affected by IBMX. Both cells are excited by forskolin. We conclude that the B1 neuron response to octopamine is likely to be mediated by cAMP, while the B2 and B3 responses are cAMP-independent.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz
Depositing User: Endre Sarvay
Date Deposited: 13 Nov 2017 16:19
Last Modified: 13 Nov 2017 16:19

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