Definition of Drosophila hemocyte subsets by cell-type specific antigens

Kurucz, Éva and Váczi, B. and Márkus, R. and Laurinyecz, Barbara and Vilmos, P. and Zsámboki, J. and Csorba, Kinga and Gateff, Elisabeth and Hultmark, D. and Andó, I. (2007) Definition of Drosophila hemocyte subsets by cell-type specific antigens. Acta Biologica Hungarica, 58 (Supple). pp. 95-111. ISSN 0236-5383

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We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.

Item Type: Article
Subjects: Q Science / természettudomány > QH Natural history / természetrajz
Depositing User: Endre Sarvay
Date Deposited: 20 Nov 2017 15:38
Last Modified: 20 Nov 2017 15:38

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