Karakaş, A. and Kaya, Aliye and Gündüz, B. (2010) The effect of pinealectomy, melatonin and leptin hormones on ovarian follicular development in female Syrian hamsters (Mesocricetus auratus). Acta Biologica Hungarica, 61 (4). pp. 380-390. ISSN 0236-5383
![]() |
Text
abiol.61.2010.4.2.pdf Restricted to Repository staff only until 31 December 2030. Download (1MB) |
Abstract
We studied the effects of melatonin and leptin hormones on ovarian follicular development in intact and pinealectomized female Syrian hamsters. We first monitored the oestrous cycle of the hamsters by the vaginal smear samples throughout a ten day period to start the injections simultaneously in all groups and performed saline, melatonin and leptin hormone injection groups for both control and pinealectomized hamsters. Then the injections were applied for four days starting the oestrus phase of the cycle and the ovaries were removed for preparation of histological analysis. We measured the diameters and the numbers of the follicles and we classified the follicles according to the number of the granulosa cell layer. Leptin hormone injection increased melatonin hormone injection decreased the number and the diameter of the follicles. The stimulating effect of the leptin hormone was more pronounced in the pinealectomized group. The results of the present study indicate that the removal of the pineal gland and leptin hormone administration are playing a stimulatory while melatonin hormone administration is playing an inhibitory role on the follicular development in female Syrian hamsters.
Item Type: | Article |
---|---|
Subjects: | Q Science / természettudomány > QH Natural history / természetrajz |
Depositing User: | Endre Sarvay |
Date Deposited: | 23 Nov 2017 15:43 |
Last Modified: | 23 Nov 2017 15:43 |
URI: | http://real.mtak.hu/id/eprint/70399 |
Actions (login required)
![]() |
Edit Item |