Serotonin transport and synthesis systems during early development of invertebrates: Functional analysis on a bivalve model

Ivashkin, E. and Khabarova, Marina and Voronezhskaya, Elena (2012) Serotonin transport and synthesis systems during early development of invertebrates: Functional analysis on a bivalve model. Acta Biologica Hungarica, 63 (Supple). pp. 217-220. ISSN 0236-5383

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Abstract

Serotonin (5.HT) is known to be functionally active during early development in both vertebrates and invertebrates. However, the presence of 5-HT and its synthesis and transport system has not yet been demonstrated in bivalve early development. The presence of 5-HT was immunochemically demonstrated at the cleavage stage of bivalve Mytilus trossulus. 5-HT level dramatically increased within all embryonic cells after incubation with 5-HTP but not after incubation with tryptophan and 5-HT. The first 5-HT uptake by specific transporter was detected at 13 hpf blastula stage only and it was restricted to one distinct cell.

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