Czompa, A. and Kovács, T. and Antus, S. (2000) Lipase-catalysed kinetic resolution of hydroxymethylchromanes. JOURNAL OF HETEROCYCLIC CHEMISTRY, 37. pp. 991-995. ISSN 0022-152X
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Abstract
An effective kinetic resolution of hydroxymethylchromanes racemic 2a and 3a has been achieved by means of enantioselective transesterification with vinyl acetate in organic solvents. The alcohols (-)-R-2a and (-)-S-3a were obtained with high optical purities (94 and 98% ee) in 70% and 38% yields, respectively. The influence of the enzyme source and the character of the solvent on the enantioselectivity were studied.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science / természettudomány > QD Chemistry / kémia > QD04 Organic chemistry / szerves kémia |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 21 Feb 2018 13:00 |
| Last Modified: | 21 Feb 2018 13:00 |
| URI: | http://real.mtak.hu/id/eprint/74872 |
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