Value of the eazyplex^® CSF direct assay in rapid diagnosis of invasive meningococcal disease – Case report

Karrasch, Matthias and Eisenach, Sven and Vogel, Ulrich and Zinke, Jan and Witte, Otto W. and Günther, Albrecht and Romeike, Bernd and Rödel, Jürgen (2018) Value of the eazyplex^® CSF direct assay in rapid diagnosis of invasive meningococcal disease – Case report. Acta Microbiologica et Immunologica Hungarica, 65 (3). pp. 309-315. ISSN 1217-8950

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Abstract

There is a need for easy-to-use molecular assays for diagnosis of invasive meningococcal disease. Here, we report the rapid identification of Neisseria meningitidis in a cerebrospinal fluid sample from a patient with purulent meningitis using a commercially available loop-mediated isothermal amplification assay, resulting in a prompt de-escalation of the initial empiric antibiotic therapy.

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