Pankovics, Péter and Boros, Ákos and Nemes, Csaba and Kapusinszky, Beatrix and Delwart, Eric and Reuter, Gábor (2018) Molecular characterization of a novel picobirnavirus in a chicken. Archives of Virology. pp. 1-4. ISSN 0304-8608
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Abstract
Picobirnaviruses (PBVs) are bisegmented viruses with a wide geographical and host species distribution. The number of novel PBV sequences has been increasing with the help of the viral metagenomics. A novel picobirnavirus strain, pbv/CHK/M3841/HUN/2011, was identified by viral metagenomics; the complete segment 1 (MH327933) and 2 (MH327934) sequences were obtained by RT-PCR from a cloacal sample of a diseased broiler breeder pullet in Hungary. Although the conserved nucleotide (e.g., ribosome binding site) and amino acid motifs (e.g., ExxRxNxxxE, S-domain of the viral capsid and motifs in the RNA-dependent RNA polymerase) were identifiable in the chicken picobirnavirus genome, the putative segment 1 showed low (< 30%) amino acid sequence identity to the corresponding proteins of marmot and dromedary PBVs, while segment 2 showed higher (< 70%) amino acid sequence identity to a wolf PBV protein sequence. This is the first full-genome picobirnavirus sequence from a broiler breeder chicken, but the pathogenicity of this virus is still questionable.
Item Type: | Article |
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Subjects: | Q Science / természettudomány > QR Microbiology / mikrobiológia > QR355 Virology / víruskutatás |
Depositing User: | Dr. Peter Pankovics |
Date Deposited: | 18 Sep 2018 07:06 |
Last Modified: | 05 Apr 2023 07:41 |
URI: | http://real.mtak.hu/id/eprint/84264 |
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