Holczer, E. and Fekete, Zoltán and Fürjes, Péter (2013) Surface modification of PDMS based microfluidic systems by tensides. MATERIALS SCIENCE FORUM, 729. pp. 361-366. ISSN 0255-5476
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Abstract
The material aspects of a polymer based microfluidic structure were characterised considering the compatibility of the system with bioanalytical applications. The polydimethylsiloxane (PDMS) based channel system is to be integrated in a full polymer photonic biosensor device developed within the European Union project P3SENS (FP7-ICT4-248304). This work is intended to define a modified material composition, which is appropriate to improve both the wettability and the non-specific protein binding characteristics of the PDMS significantly. Triton X-100 (Sigma-Aldrich) surfactant was added to the raw PDMS before polymerisation. The influence of the tenside was studied considering the polymerisation reaction, the surface characteristics and the functional applicability. To test the hydrodynamic behaviour and non-specific protein adsorption on the surfaces, phosphate buffered saline (PBS) solution and fluorescent labelled human serum albumin (HSA) was applied in a microfluidic capillary system. © (2013) Trans Tech Publications, Switzerland.
| Item Type: | Article |
|---|---|
| Additional Information: | 8th Hungarian Conference on Materials Science 9 October 2011 through 11 October 2011 Balatonkenese |
| Uncontrolled Keywords: | Silicones; surface treatment; Surface reactions; POLYMERS; POLYMERIZATION; Microchannels; Materials science; Fluidic devices; biosensors; BIOCHEMISTRY; Triton X-100; Tensides; Surface modification of PDMS; Surface characteristics; Sigma-aldrich; Protein Binding; Polymer photonics; Polymer based; Polydimethylsiloxane PDMS; Phosphate buffered saline solutions; Non-specific protein adsorption; Microfluidic structures; Micro fluidic system; Material compositions; Human serum albumins; European Union; Channel systems; Capillary system; Bioanalytical applications; Tenside; surface modification; PDMS; Microfluidics |
| Subjects: | Q Science / természettudomány > Q1 Science (General) / természettudomány általában |
| SWORD Depositor: | MTMT SWORD |
| Depositing User: | MTMT SWORD |
| Date Deposited: | 10 Jan 2014 20:27 |
| Last Modified: | 10 Jan 2014 20:27 |
| URI: | http://real.mtak.hu/id/eprint/8594 |
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