Detection of Gamma-Irradiation Effect on DNA and Protein Using Magnetic Sensor and Cyclic Voltammetry

Park, Duck-Gun and Song, Hoon and Kishore, M. B. and Vértesy, Gábor and Lee, Duk-Hyun (2013) Detection of Gamma-Irradiation Effect on DNA and Protein Using Magnetic Sensor and Cyclic Voltammetry. Journal of Nanoscience and Nanotechnology, 13 (11). pp. 7250-7253. ISSN 1533-4880 (nyomtatott); 1533-4899 (online)

Text JNano_Detection_13_7250.pdf Restricted to Repository staff only Download (927kB)

Abstract

In this study, a magnetic sensor utilizing Planar Hall Resistance (PHR) and cyclic Voltammetry (CV) for detecting the radiation effect was fabricated. Specifically, we applied in parallel a PHR sensor and CV device to monitor the irradiation effect on DNA and protein respectively. Through parallel measurements, we demonstrated that the PHR sensor and CV are sensitive enough to measure irradiation effect. The PHR voltage decreased by magnetic nanobead labeled DNA was slightly recovered after gamma ray irradiation. The behavior of cdk inhibitor protein p21 having a sandwich structure of Au/protein G/Ab/Ag/Ab was checked by monitoring the cyclic Voltammetry signal in analyzing the gamma ray irradiation effect.

Actions (login required)

Edit Item