Effects of embedded surfactants on the surface properties of PDMS; applicability for autonomous microfluidic systems

Holczer, Eszter Gabriella and Fürjes, Péter (2017) Effects of embedded surfactants on the surface properties of PDMS; applicability for autonomous microfluidic systems. MICROFLUIDICS AND NANOFLUIDICS, 21 (5). p. 81. ISSN 1613-4982

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Abstract

Controlled surface modification of the PDMS (polydimethylsiloxane) was developed and studied in this work to develop autonomous capillary-driven microfluidic system to be applied in bioanalytical devices. The characteristics of the PDMS surfaces were modified by embedding adequate surfactant molecules in the polymer matrix to be moved onto the free surface by diffusion. The change of the surface characteristics was studied considering the expected performance in autonomous biomicrofluidic applications and the influence on non-specific human blood protein binding also. The method was evaluated from technological aspects also, as the integrability of the microfluidic system, considering the previously published results critically. Compositions were defined to be adequate for fabrication autonomous capillary system with enhanced transport efficiency and moderated non-specific protein adsorption.

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